Variable RXR requirements for thyroid hormone responsiveness of endogenous genes
نویسندگان
چکیده
منابع مشابه
RXR receptor agonist suppression of thyroid function: central effects in the absence of thyroid hormone receptor.
High-affinity agonists for the retinoic acid X receptors (RXR) have pleotropic effects when administered to humans. These include induction of hypertriglyceridemia and hypothyroidism. We determined the effect of a novel high-affinity RXR agonist with potent antihyperglycemic effects on thyroid function of female Zucker diabetic rats and nondiabetic littermates and in db/db mice. In both nondiab...
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Thyroid hormone receptors (TRs) are ligand-regulatable transcription factors. Currently, little is known about the expression of TRs or other nuclear hormone receptors during the cell cycle. We thus developed a stable expression system to express green fluorescent protein-TR in HeLa cells under tetracycline regulation, and studied TR expression during the cell cycle by laser scanning cytometry....
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Thyroid hormone receptors (TRs) are ligand-regulatable transcription factors. Currently, little is known about the expression of TRs or other nuclear hormone receptors during the cell cycle. We thus developed a stable expression system to express green fluorescent protein-TRbeta in HeLa cells under tetracycline regulation, and studied TR expression during the cell cycle by laser scanning cytome...
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ژورنال
عنوان ژورنال: Molecular and Cellular Endocrinology
سال: 2007
ISSN: 0303-7207
DOI: 10.1016/j.mce.2006.11.004